Kynurenine 3 monooxygenase (KMO) (NM_003679) Human Recombinant Protein
Product Specifications
Background
This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease. [provided by RefSeq, Oct 2011]
Overview
Recombinant protein of human kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO), full length, with C-terminal DDK tag, expressed in sf9, 20ug
Synonyms
DJ317G22.1
Gene ID
8564
UniProt
O15229, A8K693
Accession Number mRNA
NM_003679
Chromosomal Location
1q43
Expression System
Sf9
Tag
C-DDK
Related Pathways
Metabolic pathways, Tryptophan metabolism
Field of Research
Metabolic pathways, Tryptophan metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
55.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KMO
Species
Human
Protein ID
NP_003670
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8564
Uniprot URL
https://www.uniprot.org/uniprot/O15229
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003679
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003670
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