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Eph receptor A5 (EPHA5) (NM_004439) Human Recombinant Protein

Product Specifications

Background

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Aug 2013]

Synonyms

CEK7; EHK-1; EHK1; EK7; HEK7; TYRO4

Gene ID

2044

UniProt

P54756, A0A384MU00, B7ZKJ3, Q59FT4

Accession Number mRNA

NM_004439

Chromosomal Location

4q13.1-q13.2

Expression System

Sf9

Tag

C-DDK

Related Pathways

Axon guidance

Field of Research

Axon guidance

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase, Transmembrane

Molecular Weight

60.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EPHA5

Species

Human

Protein ID

NP_004430

Overview

Recombinant protein of human EPH receptor A5 (EPHA5), transcript variant 1, residues 25-573aa, with C-terminal DDK tag, expressed in sf9, 20ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2044

Uniprot URL

https://www.uniprot.org/uniprot/P54756

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004439

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004430

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