SH3GL2 (NM_003026) Human Recombinant Protein
Product Specifications
Background
Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human SH3-domain GRB2-like 2 (SH3GL2), full length, with C-terminal DDK tag, expressed in sf9, 20ug
Synonyms
CNSA2; EEN-B1; SH3D2A; SH3P4
Gene ID
6456
UniProt
Q99962, Q7Z376
Accession Number mRNA
NM_003026
Chromosomal Location
9p22.2
Expression System
Sf9
Tag
C-DDK
Related Pathways
Endocytosis
Field of Research
Endocytosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
Molecular Weight
40
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SH3GL2
Species
Human
Protein ID
NP_003017
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6456
Uniprot URL
https://www.uniprot.org/uniprot/Q99962
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003026
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003017
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