CCN2 (NM_001901) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]
Overview
Recombinant protein of human connective tissue growth factor (CTGF), residues 27-349aa, secretory expressed with GP67 signal peptide, with C-terminal DDK tag, expressed in sf9, 20ug
Synonyms
CTGF; HCS24; IGFBP8; NOV2
Gene ID
1490
UniProt
P29279, Q5M8T4
Accession Number mRNA
NM_001901
Chromosomal Location
6q23.2
Expression System
Sf9
Tag
C-DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
35.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CCN2
Species
Human
Protein ID
NP_001892
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1490
Uniprot URL
https://www.uniprot.org/uniprot/P29279
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001901
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001892
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