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CCN2 (NM_001901) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]

Overview

Recombinant protein of human connective tissue growth factor (CTGF), residues 27-349aa, secretory expressed with GP67 signal peptide, with C-terminal DDK tag, expressed in sf9, 20ug

Synonyms

CTGF; HCS24; IGFBP8; NOV2

Gene ID

1490

UniProt

P29279, Q5M8T4

Accession Number mRNA

NM_001901

Chromosomal Location

6q23.2

Expression System

Sf9

Tag

C-DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein

Molecular Weight

35.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CCN2

Species

Human

Protein ID

NP_001892

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1490

Uniprot URL

https://www.uniprot.org/uniprot/P29279

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001901

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001892

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