KDM5A (NM_001042603) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013]
Overview
Purified recombinant protein of Human lysine (K) -specific demethylase 5A (KDM5A), full length, with C-terminal DDK tag, expressed in sf9 insect cells
Synonyms
RBBP-2; RBBP2; RBP2
Gene ID
5927
UniProt
P29375
Accession Number mRNA
NM_001042603
Chromosomal Location
12p13.33
Expression System
Sf9
Tag
C-DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
Function
Druggable Genome
Molecular Weight
192 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KDM5A
Species
Human
Protein ID
NP_001036068
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5927
Uniprot URL
https://www.uniprot.org/uniprot/P29375
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001042603
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001036068
Curated Selection
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