AATF (NM_012138) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human apoptosis antagonizing transcription factor (AATF), full length, with C-terminal DDK tag, expressed in sf9, 20ug

Synonyms

BFR2; CHE-1; CHE1; DED

Gene ID

26574

UniProt

Q9NY61

Accession Number mRNA

NM_012138

Chromosomal Location

17q12

Expression System

Sf9

Tag

C-DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.

Function

Druggable Genome, Stem cell - Pluripotency, Transcription Factors

Molecular Weight

63 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.