MAPRE1 (NM_012325) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of human microtubule-associated protein, RP/EB family, member 1 (MAPRE1), full length, with C-terminal DDK tag, expressed in sf9, 20ug
Synonyms
EB1
Gene ID
22919
UniProt
Q15691
Accession Number mRNA
NM_012325
Chromosomal Location
20q11.21
Expression System
Sf9
Tag
C-DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
29.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MAPRE1
Species
Human
Protein ID
NP_036457
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22919
Uniprot URL
https://www.uniprot.org/uniprot/Q15691
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012325
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036457
Frequently Asked Questions
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