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MAPRE1 (NM_012325) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of human microtubule-associated protein, RP/EB family, member 1 (MAPRE1), full length, with C-terminal DDK tag, expressed in sf9, 20ug

Synonyms

EB1

Gene ID

22919

UniProt

Q15691

Accession Number mRNA

NM_012325

Chromosomal Location

20q11.21

Expression System

Sf9

Tag

C-DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

29.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MAPRE1

Species

Human

Protein ID

NP_036457

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/22919

Uniprot URL

https://www.uniprot.org/uniprot/Q15691

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_012325

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_036457

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