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Neurotrophin 3 (NTF3) (NM_001102654) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008]

Synonyms

HDNF; NGF-2; NGF2; NT-3; NT3

Gene ID

4908

UniProt

P20783

Accession Number mRNA

NM_001102654

Chromosomal Location

12p13.31

Expression System

E. coli

Tag

Tag Free

Related Pathways

MAPK signaling pathway, Neurotrophin signaling pathway

Field of Research

MAPK signaling pathway, Neurotrophin signaling pathway

Concentration

Resuspend the protein to the desired concentration in proper buffer.

Endotoxin

< 0.1 EU per 1 µg of the protein by the LAL

Purity

>95% as determined by SDS-PAGE and Coomassie blue staining

Form

Lyophilized

Buffer

Lyophilized from a sterile solution containing 20 mM phosphate buffer, pH7.4.

Function

Druggable Genome, Secreted Protein

Molecular Weight

13.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NTF3

Species

Human

Protein ID

NP_001096124

Overview

Recombinant protein of human Neurotrophin-3 (NT3) produced in E. coli.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4908

Uniprot URL

https://www.uniprot.org/uniprot/P20783

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001102654

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001096124

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