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MRP8 (S100A8) (NM_002964) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

Overview

Purified recombinant protein of Human S100 calcium binding protein A8 (S100A8), full length, with C-terminal His tag, expressed in E.coli, 50ug

Synonyms

60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8

Gene ID

6279

UniProt

P05109

Accession Number mRNA

NM_002964

Chromosomal Location

1q21.3

Expression System

E. coli

Tag

C-His

Concentration

Concentration is determined by microplate BCA method

Purity

> 90% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% Glycerol.

Molecular Weight

11.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

S100A8

Species

Human

Protein ID

NP_002955

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6279

Uniprot URL

https://www.uniprot.org/uniprot/P05109

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002964

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002955

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