Hsp60 (HSPD1) (NM_199440) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]
Synonyms
CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13
Gene ID
3329
UniProt
P10809, A0A024R3X4
Accession Number mRNA
NM_199440
Chromosomal Location
2q33.1
Expression System
E. coli
Tag
N-His
Related Pathways
RNA degradation, Type I diabetes mellitus
Field of Research
RNA degradation, Type I diabetes mellitus
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol
Function
Druggable Genome, Stem cell - Pluripotency
Molecular Weight
61.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HSPD1
Species
Human
Protein ID
NP_955472
Overview
Recombinant protein of human heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3329
Uniprot URL
https://www.uniprot.org/uniprot/P10809
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_199440
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_955472
Curated Selection
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