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Hsp60 (HSPD1) (NM_199440) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]

Overview

Recombinant protein of human heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13

Gene ID

3329

UniProt

P10809, A0A024R3X4

Accession Number mRNA

NM_199440

Chromosomal Location

2q33.1

Expression System

E. coli

Tag

N-His

Related Pathways

RNA degradation, Type I diabetes mellitus

Field of Research

RNA degradation, Type I diabetes mellitus

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol

Function

Druggable Genome, Stem cell - Pluripotency

Molecular Weight

61.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HSPD1

Species

Human

Protein ID

NP_955472

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3329

Uniprot URL

https://www.uniprot.org/uniprot/P10809

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_199440

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_955472

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