Mitofilin (IMMT) (NM_006839) Human Recombinant Protein
Product Specifications
Background
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180) .[UniProtKB/Swiss-Prot Function]
Synonyms
HMP; Mic60; MICOS60; MINOS2; P87; P87/89; P89; PIG4; PIG52
Gene ID
10989
UniProt
Q16891
Accession Number mRNA
NM_006839
Chromosomal Location
2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg
Molecular Weight
83.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IMMT
Species
Human
Protein ID
NP_006830
Overview
Recombinant protein of human inner membrane protein, mitochondrial (IMMT), nuclear gene encoding mitochondrial protein, transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10989
Uniprot URL
https://www.uniprot.org/uniprot/Q16891
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006839
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006830
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