PPP2R5D (NM_006245) Human Recombinant Protein
Product Specifications
Background
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Synonyms
B56D; B56delta; MRD35
Gene ID
5528
UniProt
Q14738, A0A024RD11
Accession Number mRNA
NM_006245
Chromosomal Location
6p21.1
Expression System
E. coli
Tag
N-His
Related Pathways
Oocyte meiosis, Wnt signaling pathway
Field of Research
Oocyte meiosis, Wnt signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg
Function
Phosphatase
Molecular Weight
70 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PPP2R5D
Species
Human
Protein ID
NP_006236
Overview
Recombinant protein of human protein phosphatase 2, regulatory subunit B', delta (PPP2R5D), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5528
Uniprot URL
https://www.uniprot.org/uniprot/Q14738
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006245
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006236
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