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PPP2R5D (NM_006245) Human Recombinant Protein

Product Specifications

Background

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Synonyms

B56D; B56delta; MRD35

Gene ID

5528

UniProt

Q14738, A0A024RD11

Accession Number mRNA

NM_006245

Chromosomal Location

6p21.1

Expression System

E. coli

Tag

N-His

Related Pathways

Oocyte meiosis, Wnt signaling pathway

Field of Research

Oocyte meiosis, Wnt signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg

Function

Phosphatase

Molecular Weight

70 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PPP2R5D

Species

Human

Protein ID

NP_006236

Overview

Recombinant protein of human protein phosphatase 2, regulatory subunit B', delta (PPP2R5D), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5528

Uniprot URL

https://www.uniprot.org/uniprot/Q14738

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006245

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006236

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