TRIM27 (NM_006510) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human tripartite motif containing 27 (TRIM27), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
RFP; RNF76
Gene ID
5987
UniProt
P14373, A0A1U9X8R9
Accession Number mRNA
NM_006510
Chromosomal Location
6p22.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg
Function
Druggable Genome, Transcription Factors
Molecular Weight
58.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TRIM27
Species
Human
Protein ID
NP_006501
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5987
Uniprot URL
https://www.uniprot.org/uniprot/P14373
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006510
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006501
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