ANP (NPPA) (NM_006172) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1. [provided by RefSeq, Oct 2015]
Overview
Recombinant protein of human natriuretic peptide precursor A (NPPA), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
ANF; ANP; ATFB6; ATRST2; CDD; CDD-ANF; CDP; PND
Gene ID
4878
UniProt
P01160
Accession Number mRNA
NM_006172
Chromosomal Location
1p36.22
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Function
Secreted Protein, Transmembrane
Molecular Weight
16.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NPPA
Species
Human
Protein ID
NP_006163
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4878
Uniprot URL
https://www.uniprot.org/uniprot/P01160
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006172
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006163
Frequently Asked Questions
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