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ANP (NPPA) (NM_006172) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1. [provided by RefSeq, Oct 2015]

Overview

Recombinant protein of human natriuretic peptide precursor A (NPPA), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

ANF; ANP; ATFB6; ATRST2; CDD; CDD-ANF; CDP; PND

Gene ID

4878

UniProt

P01160

Accession Number mRNA

NM_006172

Chromosomal Location

1p36.22

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

Function

Secreted Protein, Transmembrane

Molecular Weight

16.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NPPA

Species

Human

Protein ID

NP_006163

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4878

Uniprot URL

https://www.uniprot.org/uniprot/P01160

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006172

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006163

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