TRBP (TARBP2) (NM_004178) Human Recombinant Protein
Product Specifications
Background
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]
Synonyms
LOQS; TRBP; TRBP1; TRBP2
Gene ID
6895
UniProt
Q15633
Accession Number mRNA
NM_004178
Chromosomal Location
12q13.13
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Function
Stem cell - Pluripotency
Molecular Weight
39
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TARBP2
Species
Human
Protein ID
NP_004169
Overview
Recombinant protein of human TAR (HIV-1) RNA binding protein 2 (TARBP2), transcript variant 3, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6895
Uniprot URL
https://www.uniprot.org/uniprot/Q15633
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004178
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004169
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