TRMT12 (NM_017956) Human Recombinant Protein
Product Specifications
Background
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006) .[supplied by OMIM, Mar 2008]
Synonyms
TRM12; TYW2
Gene ID
55039
UniProt
Q53H54
Accession Number mRNA
NM_017956
Chromosomal Location
8q24.13
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Molecular Weight
50.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TRMT12
Species
Human
Protein ID
NP_060426
Overview
Recombinant protein of human tRNA methyltransferase 12 homolog (S. cerevisiae) (TRMT12), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55039
Uniprot URL
https://www.uniprot.org/uniprot/Q53H54
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017956
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060426
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