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KMT5A (NM_020382) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a protein-lysine N-methyltransferase that can monomethylate Lys-20 of histone H4 to effect transcriptional repression of some genes. The encoded protein is required for cell proliferation and plays a role in chromatin condensation. [provided by RefSeq, May 2016]

Overview

Recombinant protein of human SET domain containing (lysine methyltransferase) 8 (SETD8), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

PR-Set7; PR/SET07; SET07; SET8; SETD8

Gene ID

387893

UniProt

Q9NQR1

Accession Number mRNA

NM_020382

Chromosomal Location

12q24.31

Expression System

E. coli

Tag

N-His

Related Pathways

Lysine degradation

Field of Research

Lysine degradation

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

Function

Druggable Genome

Molecular Weight

42.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

KMT5A

Species

Human

Protein ID

NP_065115

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/387893

Uniprot URL

https://www.uniprot.org/uniprot/Q9NQR1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_020382

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_065115

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