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H2AC1 (NM_170745) Human Recombinant Protein

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]

Synonyms

BA317E16.2; H2AA; H2AFR; HIST1H2AA; TH2A

Gene ID

221613

UniProt

Q96QV6

Accession Number mRNA

NM_170745

Chromosomal Location

6p22.2

Expression System

E. coli

Tag

N-His

Related Pathways

Systemic lupus erythematosus

Field of Research

Systemic lupus erythematosus

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

Molecular Weight

14.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

H2AC1

Species

Human

Protein ID

NP_734466

Overview

Recombinant protein of human histone cluster 1, H2aa (HIST1H2AA), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/221613

Uniprot URL

https://www.uniprot.org/uniprot/Q96QV6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_170745

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_734466

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