GLS2 (NM_013267) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
Overview
Recombinant protein of human glutaminase 2 (liver, mitochondrial) (GLS2), nuclear gene encoding mitochondrial protein, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
GA; GLS; hLGA; LGA
Gene ID
27165
UniProt
Q9UI32
Accession Number mRNA
NM_013267
Chromosomal Location
12q13.3
Expression System
E. coli
Tag
N-His
Related Pathways
Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, D-Glutamine and D-glutamate metabolism, Metabolic pathways, Nitrogen metabolism
Field of Research
Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, D-Glutamine and D-glutamate metabolism, Metabolic pathways, Nitrogen metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Molecular Weight
66.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GLS2
Species
Human
Protein ID
NP_037399
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27165
Uniprot URL
https://www.uniprot.org/uniprot/Q9UI32
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013267
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037399
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