Nkx2.2 (NKX2-2) (NM_002509) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human NK2 homeobox 2 (NKX2-2), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
NKX2.2; NKX2B
Gene ID
4821
UniProt
O95096
Accession Number mRNA
NM_002509
Chromosomal Location
20p11.22
Expression System
E. coli
Tag
N-His
Related Pathways
Maturity onset diabetes of the young
Field of Research
Maturity onset diabetes of the young
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Function
Transcription Factors
Molecular Weight
30 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NKX2-2
Species
Human
Protein ID
NP_002500
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4821
Uniprot URL
https://www.uniprot.org/uniprot/O95096
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002509
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002500
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