KLF10 (NM_005655) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Overview
Recombinant protein of human Kruppel-like factor 10 (KLF10), transcript variant 1, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
EGR-alpha; EGRA; TIEG; TIEG1
Gene ID
7071
UniProt
Q13118
Accession Number mRNA
NM_005655
Chromosomal Location
8q22.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Function
Druggable Genome, Transcription Factors
Molecular Weight
52.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KLF10
Species
Human
Protein ID
NP_005646
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7071
Uniprot URL
https://www.uniprot.org/uniprot/Q13118
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005655
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005646
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