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Cytokeratin 14 (KRT14) (NM_000526) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human keratin 14 (KRT14), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

CK14; EBS3; EBS4; K14; NFJ

Gene ID

3861

UniProt

P02533

Accession Number mRNA

NM_000526

Chromosomal Location

17q21.2

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

Molecular Weight

51.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

KRT14

Species

Human

Protein ID

NP_000517

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3861

Uniprot URL

https://www.uniprot.org/uniprot/P02533

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000526

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000517

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