UBE2G2 (NM_182688) Human Recombinant Protein
Product Specifications
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Overview
Recombinant protein of human ubiquitin-conjugating enzyme E2G 2 (UBE2G2), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
UBC7
Gene ID
7327
UniProt
P60604
Accession Number mRNA
NM_182688
Chromosomal Location
21q22.3
Expression System
E. coli
Tag
N-His
Related Pathways
Parkinson's disease, Ubiquitin mediated proteolysis
Field of Research
Parkinson's disease, Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
15.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UBE2G2
Species
Human
Protein ID
NP_872630
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7327
Uniprot URL
https://www.uniprot.org/uniprot/P60604
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_182688
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_872630
Frequently Asked Questions
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