SLC25A31 (NM_031291) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the ADP/ATP carrier family of proteins that exchange cytosolic ADP for matrix ATP in the mitochondria. Cells over-expressing this gene have been shown to display an anti-apoptotic phenotype. This protein is also thought to play a role in spermatogenesis, where it is believed to associate with a part of the flagellar cytoskeleton and with glycolytic enzymes. Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Overview
Recombinant protein of human solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 (SLC25A31), nuclear gene encoding mitochondrial protein, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
AAC4; ANT 4; ANT4; SFEC35kDa
Gene ID
83447
UniProt
Q9H0C2
Accession Number mRNA
NM_031291
Chromosomal Location
4q28.1
Expression System
E. coli
Tag
N-His
Related Pathways
Calcium signaling pathway, Huntington's disease, Parkinson's disease
Field of Research
Calcium signaling pathway, Huntington's disease, Parkinson's disease
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome, Transmembrane
Molecular Weight
34.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SLC25A31
Species
Human
Protein ID
NP_112581
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/83447
Uniprot URL
https://www.uniprot.org/uniprot/Q9H0C2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_031291
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_112581
Frequently Asked Questions
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