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SLC25A31 (NM_031291) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the ADP/ATP carrier family of proteins that exchange cytosolic ADP for matrix ATP in the mitochondria. Cells over-expressing this gene have been shown to display an anti-apoptotic phenotype. This protein is also thought to play a role in spermatogenesis, where it is believed to associate with a part of the flagellar cytoskeleton and with glycolytic enzymes. Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Overview

Recombinant protein of human solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 (SLC25A31), nuclear gene encoding mitochondrial protein, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

AAC4; ANT 4; ANT4; SFEC35kDa

Gene ID

83447

UniProt

Q9H0C2

Accession Number mRNA

NM_031291

Chromosomal Location

4q28.1

Expression System

E. coli

Tag

N-His

Related Pathways

Calcium signaling pathway, Huntington's disease, Parkinson's disease

Field of Research

Calcium signaling pathway, Huntington's disease, Parkinson's disease

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome, Transmembrane

Molecular Weight

34.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SLC25A31

Species

Human

Protein ID

NP_112581

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/83447

Uniprot URL

https://www.uniprot.org/uniprot/Q9H0C2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_031291

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_112581

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