FOLR3 (NM_000804) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Overview
Recombinant protein of human folate receptor 3 (gamma) (FOLR3), with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
FR-G; FR-gamma; FRgamma; gamma-hFR
Gene ID
2352
UniProt
P41439
Accession Number mRNA
NM_000804
Chromosomal Location
11q13.4
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome, Secreted Protein
Molecular Weight
27.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FOLR3
Species
Human
Protein ID
NP_000795
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2352
Uniprot URL
https://www.uniprot.org/uniprot/P41439
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000804
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000795
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