FOLR3 (NM_000804) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Overview

Recombinant protein of human folate receptor 3 (gamma) (FOLR3), with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

FR-G; FR-gamma; FRgamma; gamma-hFR

Gene ID

2352

UniProt

P41439

Accession Number mRNA

NM_000804

Chromosomal Location

11q13.4

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome, Secreted Protein

Molecular Weight

27.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.