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WARS2 (NM_015836) Human Recombinant Protein

Product Specifications

Background

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Synonyms

MtTrpRS; NEMMLAS; TrpRS

Gene ID

10352

UniProt

Q9UGM6

Accession Number mRNA

NM_015836

Chromosomal Location

1p12

Expression System

E. coli

Tag

N-His

Related Pathways

Aminoacyl-tRNA biosynthesis, Tryptophan metabolism

Field of Research

Aminoacyl-tRNA biosynthesis, Tryptophan metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome

Molecular Weight

37.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

WARS2

Species

Human

Protein ID

NP_056651

Overview

Recombinant protein of human tryptophanyl tRNA synthetase 2, mitochondrial (WARS2), nuclear gene encoding mitochondrial protein, transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10352

Uniprot URL

https://www.uniprot.org/uniprot/Q9UGM6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_015836

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_056651

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