WARS2 (NM_015836) Human Recombinant Protein
Product Specifications
Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms
MtTrpRS; NEMMLAS; TrpRS
Gene ID
10352
UniProt
Q9UGM6
Accession Number mRNA
NM_015836
Chromosomal Location
1p12
Expression System
E. coli
Tag
N-His
Related Pathways
Aminoacyl-tRNA biosynthesis, Tryptophan metabolism
Field of Research
Aminoacyl-tRNA biosynthesis, Tryptophan metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
37.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
WARS2
Species
Human
Protein ID
NP_056651
Overview
Recombinant protein of human tryptophanyl tRNA synthetase 2, mitochondrial (WARS2), nuclear gene encoding mitochondrial protein, transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10352
Uniprot URL
https://www.uniprot.org/uniprot/Q9UGM6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015836
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056651
Curated Selection
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