CBX2 (NM_032647) Human Recombinant Protein

Product Specifications

Background

This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010]

Overview

Purified recombinant protein of Human chromobox homolog 2 (CBX2), transcript variant 2, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

CDCA6; M33; SRXY5

Gene ID

84733

UniProt

Q14781

Accession Number mRNA

NM_032647

Chromosomal Location

17q25.3

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

Function

Transcription Factors

Molecular Weight

23.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.