CBX2 (NM_032647) Human Recombinant Protein
Product Specifications
Background
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010]
Synonyms
CDCA6; M33; SRXY5
Gene ID
84733
UniProt
Q14781
Accession Number mRNA
NM_032647
Chromosomal Location
17q25.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Function
Transcription Factors
Molecular Weight
23.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CBX2
Species
Human
Protein ID
NP_116036
Overview
Purified recombinant protein of Human chromobox homolog 2 (CBX2), transcript variant 2, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/84733
Uniprot URL
https://www.uniprot.org/uniprot/Q14781
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_032647
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_116036
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