HOXB5 (NM_002147) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008]
Synonyms
HHO.C10; HOX2; Hox2.1; HOX2A; HU-1
Gene ID
3215
UniProt
P09067
Accession Number mRNA
NM_002147
Chromosomal Location
17q21.32
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Function
Transcription Factors
Molecular Weight
29.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HOXB5
Species
Human
Protein ID
NP_002138
Overview
Purified recombinant protein of Human homeobox B5 (HOXB5), with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3215
Uniprot URL
https://www.uniprot.org/uniprot/P09067
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002147
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002138
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