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GCAP3 (GUCA1C) (NM_005459) Human Recombinant Protein

Product Specifications

Background

Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca (2+) -sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human guanylate cyclase activator 1C (GUCA1C), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

GCAP3

Gene ID

9626

UniProt

O95843

Accession Number mRNA

NM_005459

Chromosomal Location

3q13.13

Expression System

E. coli

Tag

N-His

Related Pathways

Olfactory transduction

Field of Research

Olfactory transduction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

Molecular Weight

23.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GUCA1C

Species

Human

Protein ID

NP_005450

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9626

Uniprot URL

https://www.uniprot.org/uniprot/O95843

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005459

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005450

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