SCDGFB (PDGFD) (NM_025208) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]
Synonyms
IEGF; MSTP036; SCDGF-B; SCDGFB
Gene ID
80310
UniProt
Q9GZP0
Accession Number mRNA
NM_025208
Chromosomal Location
11q22.3
Expression System
E. coli
Tag
N-His
Related Pathways
Focal adhesion, Gap junction, Melanoma, Prostate cancer, Regulation of actin cytoskeleton
Field of Research
Focal adhesion, Gap junction, Melanoma, Prostate cancer, Regulation of actin cytoskeleton
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
28254885
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome, Secreted Protein
Molecular Weight
40.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PDGFD
Species
Human
Protein ID
NP_079484
Overview
Purified recombinant protein of Human platelet derived growth factor D (PDGFD), transcript variant 1, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/80310
Uniprot URL
https://www.uniprot.org/uniprot/Q9GZP0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025208
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079484
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