RAD51C (NM_002876) Human Recombinant Protein
Selected Variant
PH31958E1
Size: 50 µg
Product Specifications
Background
This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Overview
Purified recombinant protein of Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
BROVCA3; FANCO; R51H3; RAD51L2
Gene ID
5889
UniProt
O43502
Accession Number mRNA
NM_002876
Chromosomal Location
17q22
Expression System
E. coli
Tag
N-His
Related Pathways
Homologous recombination
Field of Research
Homologous recombination
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
14.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RAD51C
Species
Human
Protein ID
NP_002867
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5889
Uniprot URL
https://www.uniprot.org/uniprot/O43502
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002876
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002867
Price
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