SFRP4 (NM_003014) Human Recombinant Protein
Product Specifications
Background
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human secreted frizzled-related protein 4 (SFRP4), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
FRP-4; FRPHE; FRZB-2; PYL; sFRP-4
Gene ID
6424
UniProt
Q6FHJ7
Accession Number mRNA
NM_003014
Chromosomal Location
7p14.1
Expression System
E. coli
Tag
N-His
Related Pathways
Wnt signaling pathway
Field of Research
Wnt signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway
Molecular Weight
39.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SFRP4
Species
Human
Protein ID
NP_003005
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6424
Uniprot URL
https://www.uniprot.org/uniprot/Q6FHJ7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003014
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003005
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