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SFRP4 (NM_003014) Human Recombinant Protein

Product Specifications

Background

Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human secreted frizzled-related protein 4 (SFRP4), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

FRP-4; FRPHE; FRZB-2; PYL; sFRP-4

Gene ID

6424

UniProt

Q6FHJ7

Accession Number mRNA

NM_003014

Chromosomal Location

7p14.1

Expression System

E. coli

Tag

N-His

Related Pathways

Wnt signaling pathway

Field of Research

Wnt signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway

Molecular Weight

39.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SFRP4

Species

Human

Protein ID

NP_003005

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6424

Uniprot URL

https://www.uniprot.org/uniprot/Q6FHJ7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003014

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003005

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