KIAA0020 (PUM3) (NM_014878) Human Recombinant Protein
Product Specifications
Background
Inhibits the poly (ADP-ribosyl) ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress (PubMed:21266351) . Binds to double-stranded RNA or DNA without sequence specificity (PubMed:25512524) . Involved in development of the eye and of primordial germ cells (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human KIAA0020 (KIAA0020), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
HA-8; HLA-HA8; KIAA0020; PEN; PUF-A; PUF6; XTP5
Gene ID
9933
UniProt
Q15397
Accession Number mRNA
NM_014878
Chromosomal Location
9p24.2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Weight
73.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PUM3
Species
Human
Protein ID
NP_055693
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9933
Uniprot URL
https://www.uniprot.org/uniprot/Q15397
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014878
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055693
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