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KIAA0020 (PUM3) (NM_014878) Human Recombinant Protein

Product Specifications

Background

Inhibits the poly (ADP-ribosyl) ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress (PubMed:21266351) . Binds to double-stranded RNA or DNA without sequence specificity (PubMed:25512524) . Involved in development of the eye and of primordial germ cells (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human KIAA0020 (KIAA0020), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

HA-8; HLA-HA8; KIAA0020; PEN; PUF-A; PUF6; XTP5

Gene ID

9933

UniProt

Q15397

Accession Number mRNA

NM_014878

Chromosomal Location

9p24.2

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

Molecular Weight

73.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PUM3

Species

Human

Protein ID

NP_055693

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9933

Uniprot URL

https://www.uniprot.org/uniprot/Q15397

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014878

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055693

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