GNPAT (NM_014236) Human Recombinant Protein

Product Specifications

Background

This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

Overview

Purified recombinant protein of Human glyceronephosphate O-acyltransferase (GNPAT), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

DAP-AT; DAPAT; DHAPAT; RCDP2

Gene ID

8443

UniProt

O15228

Accession Number mRNA

NM_014236

Chromosomal Location

1q42.2

Expression System

E. coli

Tag

N-His

Related Pathways

Glycerophospholipid metabolism

Field of Research

Glycerophospholipid metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome

Molecular Weight

77 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.