UBE2E3 (NM_006357) Human Recombinant Protein
Product Specifications
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013]
Synonyms
UBCH9; UbcM2
Gene ID
10477
UniProt
Q969T4
Accession Number mRNA
NM_006357
Chromosomal Location
2q31.3
Expression System
E. coli
Tag
N-His
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Weight
22.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UBE2E3
Species
Human
Protein ID
NP_006348
Overview
Purified recombinant protein of Human ubiquitin-conjugating enzyme E2E 3 (UBE2E3), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10477
Uniprot URL
https://www.uniprot.org/uniprot/Q969T4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006357
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006348
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6383895-01 0.1 mL
KRT20 (Keratin, Type I Cytoskeletal 20, Cytokeratin-20, CK-20, Keratin-20, K20, Protein IT, MGC35423) APC
Ask
View Details MBS6383895-02 5x 0.1 mL
KRT20 (Keratin, Type I Cytoskeletal 20, Cytokeratin-20, CK-20, Keratin-20, K20, Protein IT, MGC35423) APC
Ask
View Details