TCP1 delta (CCT4) (NM_006430) Human Recombinant Protein
Product Specifications
Background
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]) .[supplied by OMIM, Mar 2008]
Synonyms
CCT-DELTA; Cctd; SRB
Gene ID
10575
UniProt
P50991
Accession Number mRNA
NM_006430
Chromosomal Location
2p15
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
57.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CCT4
Species
Human
Protein ID
NP_006421
Overview
Purified recombinant protein of Human chaperonin containing TCP1, subunit 4 (delta) (CCT4), with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10575
Uniprot URL
https://www.uniprot.org/uniprot/P50991
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006430
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006421
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