TCP1 delta (CCT4) (NM_006430) Human Recombinant Protein

Product Specifications

Background

The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]) .[supplied by OMIM, Mar 2008]

Overview

Purified recombinant protein of Human chaperonin containing TCP1, subunit 4 (delta) (CCT4), with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

CCT-DELTA; Cctd; SRB

Gene ID

10575

UniProt

P50991

Accession Number mRNA

NM_006430

Chromosomal Location

2p15

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome

Molecular Weight

57.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.