HAO1 (NM_017545) Human Recombinant Protein
Product Specifications
Background
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008]
Synonyms
GOX; GOX1; HAOX1
Gene ID
54363
UniProt
Q9UJM8, A8K058
Accession Number mRNA
NM_017545
Chromosomal Location
20p12.3
Expression System
E. coli
Tag
N-His
Related Pathways
Glyoxylate and dicarboxylate metabolism, Metabolic pathways
Field of Research
Glyoxylate and dicarboxylate metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Weight
40.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HAO1
Species
Human
Protein ID
NP_060015
Overview
Purified recombinant protein of Human hydroxyacid oxidase (glycolate oxidase) 1 (HAO1), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54363
Uniprot URL
https://www.uniprot.org/uniprot/Q9UJM8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017545
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060015
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