HES1 (NM_005524) Human Recombinant Protein
Product Specifications
Background
This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human hairy and enhancer of split 1, (Drosophila) (HES1), with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
BHLHb39; HES-1; HHL; HRY
Gene ID
3280
UniProt
Q14469
Accession Number mRNA
NM_005524
Chromosomal Location
3q29
Expression System
E. coli
Tag
N-His
Related Pathways
Maturity onset diabetes of the young, Notch signaling pathway
Field of Research
Maturity onset diabetes of the young, Notch signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transcription Factors
Molecular Weight
29.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HES1
Species
Human
Protein ID
NP_005515
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3280
Uniprot URL
https://www.uniprot.org/uniprot/Q14469
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005524
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005515
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15264252 1 Vial
Lentiviral mouse Qrich1 shRNA (UAS) - Lentiviral mouse Qrich1 shRNA (UAS, RFP) (100)
Sign In for Pricing
View Details K3412002 1.0 µg DNA
S100a13 sgRNA CRISPR Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details 
K4728707 1.0 µg DNA
Nol12 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details 
abx240026 100 µg
Transcriptional Enhancer Factor TEF-1 (TEAD1) Antibody
Sign In for Pricing
View Details