PRODH (NM_016335) Human Recombinant Protein
Product Specifications
Background
This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4) . This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Synonyms
HSPOX2; PIG6; POX; PRODH1; PRODH2; TP53I6
Gene ID
5625
UniProt
O43272
Accession Number mRNA
NM_016335
Chromosomal Location
22q11.21
Expression System
E. coli
Tag
N-His
Related Pathways
Arginine and proline metabolism, Metabolic pathways
Field of Research
Arginine and proline metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
67.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PRODH
Species
Human
Protein ID
NP_057419
Overview
Purified recombinant protein of Human proline dehydrogenase (oxidase) 1 (PRODH), nuclear gene encoding mitochondrial protein, transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5625
Uniprot URL
https://www.uniprot.org/uniprot/O43272
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016335
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057419
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