GCAP2 (GUCA1B) (NM_002098) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq, Nov 2009]
Overview
Purified recombinant protein of Human guanylate cyclase activator 1B (retina) (GUCA1B), with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
GCAP 2; GCAP2; GUCA2; RP48
Gene ID
2979
UniProt
Q9UMX6, Q7Z3V9
Accession Number mRNA
NM_002098
Chromosomal Location
6p21.1
Expression System
E. coli
Tag
N-His
Related Pathways
Olfactory transduction
Field of Research
Olfactory transduction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
23.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GUCA1B
Species
Human
Protein ID
NP_002089
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2979
Uniprot URL
https://www.uniprot.org/uniprot/Q9UMX6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002098
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002089
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