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GCAP2 (GUCA1B) (NM_002098) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq, Nov 2009]

Overview

Purified recombinant protein of Human guanylate cyclase activator 1B (retina) (GUCA1B), with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

GCAP 2; GCAP2; GUCA2; RP48

Gene ID

2979

UniProt

Q9UMX6, Q7Z3V9

Accession Number mRNA

NM_002098

Chromosomal Location

6p21.1

Expression System

E. coli

Tag

N-His

Related Pathways

Olfactory transduction

Field of Research

Olfactory transduction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome

Molecular Weight

23.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GUCA1B

Species

Human

Protein ID

NP_002089

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2979

Uniprot URL

https://www.uniprot.org/uniprot/Q9UMX6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002098

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002089

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