HES5 (NM_001010926) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer. [provided by RefSeq, Dec 2008]
Overview
Purified recombinant protein of Human hairy and enhancer of split 5 (Drosophila) (HES5), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
BHLHb38
Gene ID
388585
UniProt
Q5TA89
Accession Number mRNA
NM_001010926
Chromosomal Location
1p36.32
Expression System
E. coli
Tag
N-His
Related Pathways
Notch signaling pathway
Field of Research
Notch signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome, ES Cell Differentiation/IPS
Molecular Weight
18 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HES5
Species
Human
Protein ID
NP_001010926
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/388585
Uniprot URL
https://www.uniprot.org/uniprot/Q5TA89
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001010926
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001010926
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