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SOCS4 (NM_199421) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human suppressor of cytokine signaling 4 (SOCS4), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

SOCS7

Gene ID

122809

UniProt

Q8WXH5, Q5H9R6

Accession Number mRNA

NM_199421

Chromosomal Location

14q22.3

Expression System

E. coli

Tag

N-His

Related Pathways

Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus

Field of Research

Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome

Molecular Weight

50.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SOCS4

Species

Human

Protein ID

NP_955453

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/122809

Uniprot URL

https://www.uniprot.org/uniprot/Q8WXH5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_199421

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_955453

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