SOCS4 (NM_199421) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
SOCS7
Gene ID
122809
UniProt
Q8WXH5, Q5H9R6
Accession Number mRNA
NM_199421
Chromosomal Location
14q22.3
Expression System
E. coli
Tag
N-His
Related Pathways
Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus
Field of Research
Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
50.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SOCS4
Species
Human
Protein ID
NP_955453
Overview
Purified recombinant protein of Human suppressor of cytokine signaling 4 (SOCS4), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/122809
Uniprot URL
https://www.uniprot.org/uniprot/Q8WXH5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_199421
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_955453
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