NAT1 (NM_000662) Human Recombinant Protein
Product Specifications
Background
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Overview
Purified recombinant protein of Human N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 5, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Synonyms
AAC1; MNAT; NAT-1; NATI
Gene ID
9
UniProt
P18440
Accession Number mRNA
NM_000662
Chromosomal Location
8p22
Expression System
E. coli
Tag
N-His
Related Pathways
Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways
Field of Research
Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Weight
33.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NAT1
Species
Human
Protein ID
NP_000653
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9
Uniprot URL
https://www.uniprot.org/uniprot/P18440
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000662
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000653
Frequently Asked Questions
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