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Sumo 1 (SUMO1) (NM_001005781) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) (SUMO1), transcript variant 2, with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

DAP1; GMP1; OFC10; PIC1; SENP2; SMT3; SMT3C; SMT3H3; UBL1

Gene ID

7341

UniProt

P63165, A0A024R3Z2

Accession Number mRNA

NM_001005781

Chromosomal Location

2q33.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome, Stem cell - Pluripotency, Transcription Factors

Molecular Weight

11.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SUMO1

Species

Human

Protein ID

NP_001005781

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7341

Uniprot URL

https://www.uniprot.org/uniprot/P63165

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001005781

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001005781

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