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CDCA4 (NM_017955) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, May 2014]

Overview

Purified recombinant protein of Human cell division cycle associated 4 (CDCA4), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

HEPP; SEI-3/HEPP

Gene ID

55038

UniProt

Q9BXL8, A0A024R6P3

Accession Number mRNA

NM_017955

Chromosomal Location

14q32.33

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

ES Cell Differentiation/IPS

Molecular Weight

25.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CDCA4

Species

Human

Protein ID

NP_060425

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/55038

Uniprot URL

https://www.uniprot.org/uniprot/Q9BXL8

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_017955

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_060425

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