TOR1AIP2 (NM_022347) Human Recombinant Protein

Product Specifications

Background

One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER) . The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined. [provided by RefSeq, Mar 2017]

Overview

Purified recombinant protein of Human torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

IFRG15; LULL1; NET9

Gene ID

163590

UniProt

Q9H496

Accession Number mRNA

NM_022347

Chromosomal Location

1q25.2

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Transmembrane

Molecular Weight

15.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.