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IL28A (IFNL2) (NM_172138) Human Recombinant Protein

Product Specifications

Background

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA) . [provided by RefSeq, Jul 2008]

Synonyms

IL-28A; IL28A

Gene ID

282616

UniProt

Q8IZJ0

Accession Number mRNA

NM_172138

Chromosomal Location

19q13.2

Expression System

E. coli

Tag

N-His

Related Pathways

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Field of Research

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome, Secreted Protein, Transmembrane

Molecular Weight

22.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

IFNL2

Species

Human

Protein ID

NP_742150

Overview

Purified recombinant protein of Human interleukin 28A (interferon, lambda 2) (IL28A), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/282616

Uniprot URL

https://www.uniprot.org/uniprot/Q8IZJ0

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_172138

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_742150

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